TNFRSF10B Protein (C-His, Human)
Product Specifications
Abbreviation
TNFRSF10B
Synonyms
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, UNQ160/PRO186, ZTNFR9
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1.Loaded Recombinant Human DR5/TRAIL R2 Protein, His Tag (Cat. No. 10465-H08H) on HIS1K Biosensor, can bind Recombinant Human TRAIL/TNFSF10 Protein (Cat. No. 10409-HNAE) with an affinity constant of 0.122 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Immobilized Recombinant Human TRAIL R2 / CD262 / TNFRSF10B Protein (His Tag) (Cat: 10465-H08H) at 2 μg/mL (100 μL/well) can bind biotinylated Recombinant Human TNFSF10 / TRAIL / APO-2L / CD253 Protein (Cat: 10409-HNAE-B), the EC50 is 1.0-3.0 ng/mL (QC tested) .
Function
Met1-Glu182
Molecular Weight
The recombinant human TNFRSF10B consists of 138 amino acids and has a predicted molecular mass of 15.7 kDa. As a result of glycosylation, the apparent molecular mass of rhTNFRSF10B is approxiamtely 20-22 kDa in SDS-PAGE under reducing conditions.
Species
Human
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