SOST Protein (N-His, Human)

Product Specifications

Abbreviation

SOST

Synonyms

CDD, DAND6, SOST1, UNQ2976/PRO7455/PRO7476, VBCH

Host

HEK 293

Tag

N-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Loaded Recombinant Human LRP-6 Protein, His & AVI Tag, Avi-tag Biotinylated (Cat. No. 11968-H49H-B) on SA Biosensor, can bind Recombinant Human SOST/Sclerostin Protein, His Tag (Cat. No. 10593-H07H) with an affinity constant of 39.5 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Gln24-Tyr213

Molecular Weight

The recombinant human SOST is a monomeric protein consists of 197 amino acids and predicts a molecular mass of 22.5 kDa. As a result of glycosylation, the apparent molecular mass of rhSOST is approximately 29.9 kDa in SDS-PAGE under reducing conditions..