SIRPA Protein (C-His, Human)

Product Specifications

Abbreviation

SIRPA

Synonyms

BIT, CD172A, MFR, MYD-1, MYD1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 95 % as determined by SDS-PAGE.

Bioactivity

Immobilized Recombinant Human CD47 Protein (ECD, hFc Tag), HPLC-verified (Cat: 12283-H02H) at 2 μg/mL (100 μL/well) can bind Recombinant Human SIRP alpha/SHPS-1 Protein (ECD, SIRP alphaV2, His Tag), Amine-Labeled Biotinylated (Cat: 30014-H08H-B), the EC50 is 80-250 ng/mL (QC tested) .

Function

Met1-Arg369

Molecular Weight

The recombinant human SIRP alphaV2 consists of 350 amino acids and predicts a molecular mass of 38.6 kDa. As a result of glycosylation, it migrates as an approximately 45-55 kDa band in SDS-PAGE under reducing conditions.