PLAU Protein (C-His, Human)
Product Specifications
Abbreviation
PLAU
Synonyms
ATF, BDPLT5, QPD, u-PA, UPA, URK
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 97 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1.Immobilized human uPA at 5 μg/ml (100 μl/well) can bind mouse PLAUR with a linear range of 1.6-40 ng/ml (QC tested) . 2.Recombinant Mouse PLAUR / CD87 / uPAR Protein (His Tag) (Cat: 50160-M08H) immobilized on CM5 chip, can bind Recombinant Human Urokinase / PLAU Protein (His Tag) (Cat: 10815-H08H) with an affinity constant of 8.340 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) .
Function
Met1-Leu431
Molecular Weight
The secreted recombinant human PLAU comprises 422 amino acids with a predicted molecular mass of 46 kDa. As a result of glycosylation, rhPLAU migrates as three bands corresponding to the long A chain, B chain and unprocessed full-length PLAU with the molecular mass of 18, 32 and 50 kDa respectively in SDS-PAGE under reducing conditions.
Species
Human
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