MSLN Protein (N-human IgG1-Fc, Human)

Product Specifications

Abbreviation

MSLN

Synonyms

CAK1, MPF, SMRP

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Human MSLN / Mesothelin Protein (aa 296-580, Fc Tag) (Cat: 13128-H01H) at 2 μg/mL (100 μL/well) can bind Anti-MSLN Antibody, human IgG1, the EC50 is 10-30 ng/mL.

Function

Glu296-Gly580

Molecular Weight

The recombinant human MSLN/Fc is a disulfide-linked homodimer. The reduced monomer comprises 545 amino acids and has a predicted molecular mass of 60.7 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions due to glycosylation.