MET Protein (C-human IgG1-Fc & His, Human)
Product Specifications
Abbreviation
MET
Synonyms
AUTS9, c-Met, DA11, DFNB97, HGFR, RCCP2
Host
HEK 293
Tag
C-human IgG1-Fc & His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
Immobilized HGF Protein, Human, Recombinant (Cat:10463-HNAS) at 2 μg/mL (100 μL/well) can bind c-MET Protein, Human, Recombinant (ECD, His & hFc Tag) (Cat:10692-H03H), the EC50 is 15-70 ng/mL.
Function
Met1-Thr932
Molecular Weight
The mature recombinant human c-Met/Fc is a disulfide-linked tetramer composed of two proteolytically cleaved α and β subunits. Each α and β together with the C-terminal Fc tag consists of 1155 amino acids and has a predicted molecular mass of 129.5 (α =32.5 + Fc tagged β=97) kDa. The rh c-MET/Fc heterodimer thus migrates with apparent molecular mass of approximately 50.28 kDa and 112.61 kDa respectively in SDS-PAGE under reducing conditions due to glycosylation.
Species
Human
Curated Selection
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