LDLR Protein (C-His, Mouse)

Product Specifications

Abbreviation

LDLR

Synonyms

Hlb301, Ldlr

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

Bioactivity

Measured by its binding ability in a functional ELISA. Immobilized Rat PCSK9 at 10 μg/ml (100 μl/well) can bind biotinylated recombinant mouse LDLR . The EC50 of biotinylated mouse LDLR is 0.173 μg/ml.

Function

Met1-Arg790

Molecular Weight

The secreted recombinant mouse LDLR comprises 780 amino acids with a predicted molecular mass of 85.7 kDa. As a result of glycosylation, it migarates as approximately 120-130 kDa protein in SDS-PAGE under reducing conditions.