IL31RA Protein (C-His, Human)

Product Specifications

Abbreviation

IL31RA

Synonyms

CRL, CRL3, GLM-R, GLMR, GPL, hGLM-R, IL-31RA, PLCA2, PRO21384, UNQ6368/PRO21073/PRO21384, zcytoR17

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 85 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized human IL31RA-His (Cat: 15878-H08H) at 2 μg/mL (100 μl/well) can bind biotinylated cynomolgus IL31h (Cat: 90895-C08H), The EC50 of biotinylated cynomolgus IL31h (Cat: 90895-C08H) is 15-60 ng/mL (Routinely tested) . 2.Immobilized Recombinant Human Interleukin-31 receptor A / IL31RA Protein (His Tag) (Cat: 15878-H08H) at 2 μg/mL (100 μL/well) can bind IL31-His/Biotin (Cat: 11557-H08H-B), the EC50 is 12-36 ng/mL (Routinely tested) . 3.Recombinant Human IL-31 / IL31 Protein (His Tag) (Cat: 11557-H08H) immobilized on CM5 chip, can bind Recombinant Human Interleukin-31 receptor A / IL31RA Protein (His Tag) (Cat: 15878-H08H) with an affinity constant of 34.100 nM as determined in an SPR assay (Biacore 8K) (QC tested) . 4.Immobilized Recombinant Human Interleukin-31 receptor A / IL31RA Protein (His Tag) (Cat: 15878-H08H) at 1 μg/mL can bind Anti-IL31RA (Research Grade Nemoliz*mab Biosimilar), the EC50 is 6.5 ng/mL (Routinely tested) .