IL2RB Protein (C-His, Human)
Product Specifications
Abbreviation
IL2RB
Synonyms
CD122, IL15RB, IMD63, P70-75
Host
Baculovirus-insect Cells
Tag
C-His
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC.
Bioactivity
1.Measured by its ability to inhibit IL15-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 4.0 ng/mL of recombinant human IL-15. The ED50 for this effect is 1-6ug/ml. 2.Loaded Recombinant Human IL-2R beta/CD122 Protein, His Tag (Cat. No. 10696-H08B) on His1K Biosensor, can bind Recombinant Human IL-2 Protein, no Tag (Cat. No. 11848-HNAE2) with an affinity constant of 0.76 μM as determined in BLI assay (Sartorius Octet RED384) (QC tested) .
Function
Met1-Asp239
Molecular Weight
The recombinant human IL2RB consists of 224 amino acids and predicts a molecular mass of 26 kDa.
Species
Human
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