IL23R Protein (C-human IgG1-Fc, Rat)

Product Specifications

Abbreviation

IL23R

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Loaded Recombinant Rat IL-23 Receptor Protein, hFc Tag (Cat. No. 80395-R02H) on proA Biosensor, can bind Recombinant Mouse IL-23 Protein, His Tag (Cat. No. CT140-M08H) with an affinity constant of 18.9 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested) . 2.Recombinant Rat IL-23 Receptor Protein, hFc Tag (Cat. No. 80395-R02H) captured on Protein A chip can bind Recombinant Mouse IL-23 Protein, His Tag (Cat. No. CT140-M08H) with an affinity constant of 1.570 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) . 3.Loaded Recombinant Rabbit IL-23 Protein, His Tag (Cat. No. CT062-T08H) on HIS1K Biosensor, can bind Recombinant Rat IL-23 Receptor Protein, hFc Tag (Cat. No. 80395-R02H) with an affinity constant of 99.200 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met1-Asp367

Molecular Weight

The recombinant rat IL23R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 608 amino acids and has a predicted molecular mass of 69.4 kDa.