IL17F Protein (N-His, Human)
Product Specifications
Abbreviation
IL17F
Synonyms
CANDF6, IL-17F, IL17A, ML-1, ML1
Host
HEK 293
Tag
N-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 80 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-MALS.
Bioactivity
1. Measured by its ability to bind human IL17Ra in a functional ELISA. 2. Measured by its ability to induce IL-6 secretion by NIH‐3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is typically 5-40 ng/ml.
Function
Arg31-Gln163
Molecular Weight
The recombinant human IL17F consists of 152 amino acids and has a calculated molecular mass of 17.2 kDa. rhIL17F migrates as an approximately 24 kDa band in SDS-PAGE under reducing conditions and a 44 kDa band in non-reduced SDS-PAGE as the homodimer. The molecular weight of this protein is around 56.5 kDa verified by SEC-MALS.
Species
Human
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