IGF1R Protein (C-His-AVI, Human)

Product Specifications

Abbreviation

IGF1R

Synonyms

CD221, IGFIR, IGFR, JTK13, MGC18216

Host

HEK 293

Tag

C-His-AVI

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Loaded Anti-IGF-1R Antibody, human IgG1 on ProA Biosensor, can bind Recombinant Human IGF1R Protein, His Tag, Biotinylated (Cat. No. 10164-H49H1-B) with an affinity constant of 1.20nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Immobilized Anti-IGF-1R Antibody at 2 μg/mL (100 μL/well) can bind Recombinant Human IGF1R Protein (ECD, His & AVI Tag), Biotinylated (Cat: 10164-H49H1-B), the EC50 is 1.2-3.6 ng/mL (QC tested) .

Function

Met1-Asn932

Molecular Weight

The recombinant human IGF1R consists of 928 amino acids and predicts a molecular mass of 106.14 kDa. It migrates as an approximately 116.4 kDa and 54.1 kDa band in SDS-PAGE under reducing conditions.