IGF1R Protein (C-His-AVI, Human)

Product Specifications

Abbreviation

IGF1R

Synonyms

CD221, IGFIR, IGFR, JTK13, MGC18216

Host

HEK 293

Tag

C-His-AVI

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Loaded Anti-IGF-1R (Research Grade Teprotumumab Biosimilar) on ProA Biosensor, can bind Recombinant Human IGF1R Protein, His Tag, Biotinylated (Cat. No. 10164-H49H-B) with an affinity constant of 1.57nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Immobilized Anti-IGF-1R (Research Grade Teprotumumab Biosimilar) at 2 μg/mL (100 μL/well) can bind Recombinant Human IGF1R Protein (ECD, His & AVI Tag), Biotinylated (Cat: 10164-H49H-B), the EC50 is 1.2-3.6 ng/mL (QC tested) . 3.Immobilized Recombinant Human IGF1R Protein (ECD, His & AVI Tag), Biotinylated (Cat: 10164-H49H-B) at 1 μg/mL (100 μL/well) on streptavidin precoated (5 μg/mL, 100 μL/well) plate can bind Recombinant Human IGF1 Protein (Fc Tag) (Cat: 10598-H01H1), the EC50 is 27.5 ng/mL (Routinely tested) .

Function

Met1-Asn932

Molecular Weight

The recombinant Human IGF1R consists of 928 amino acids and predicts a molecular mass of 106.14 kDa. It migrates as an approximately 179.4 kDa、 117.9 kDa and 54.3 kDa band in SDS-PAGE under reducing conditions.

Species

Human