IFNAR2 Protein (C-His, Human)
Product Specifications
Abbreviation
IFNAR2
Synonyms
IFN-alpha-REC, IFN-R, IFN-R-2, IFNABR, IFNARB, IMD45
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1.Measured by its ability to inhibit rh IFNβ mediated protection of WISH Human amnion cells infected with vesicular stomatitis virus (VSV) to viral lysis.The EC50 for this effect is typically 1-4μg/mL (Routinely tested) . 2.Recombinant Human Interferon alpha 2 / IFNA2 Protein (K46R, Fc Tag) (Cat: 13833-H02H) captured on CM5 chip, can bind Recombinant Human IFNAR2 / IFNABR Protein (His Tag) (Cat: 10359-H08H) with an affinity constant of 1.190 μM as determined in an SPR assay (Biacore 8K) (Routinely tested) .
Function
Met1-Lys243
Molecular Weight
The recombinant human IFNAR2 consists of 228 amino acids and predicts a molecular mass of 26.2 kDa. As a result of glycosylation, the rh IFNAR2 migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions.
Species
Human
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