GDF15 Protein (N-human IgG1-Fc, Human)
Product Specifications
Abbreviation
GDF15
Synonyms
GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
Host
HEK 293
Tag
N-human IgG1-Fc
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ≥ 95 % as determined by SEC-MALS (Routinely tested) .
Bioactivity
Immobilized Recombinant Human GDF-15 Protein (Fc Tag) (Cat: 10936-H01H1) at 2 μg/mL (100 μL/well) can bind Recombinant Human GFRAL Protein (His Tag) (Cat:27245-H08H), the EC50 is 10-30 ng/mL (QC tested) .
Function
Ala197-Ile308
Molecular Weight
The recombinant Human GDF-15 comprises 575 amino acids and has a predicted molecular mass of 62.5 kDa. It migrates as an approximately 64.8 kDa band in SDS-PAGE under reducing conditions. The molecular weight of this protein is around 134.5 kDa verified by SEC-MALS (Routinely tested) .
Species
Human
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