GDF15 Protein (N-human IgG1-Fc, Human)

Product Specifications

Abbreviation

GDF15

Synonyms

GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ≥ 95 % as determined by SEC-MALS (Routinely tested) .

Bioactivity

Immobilized Recombinant Human GDF-15 Protein (Fc Tag) (Cat: 10936-H01H1) at 2 μg/mL (100 μL/well) can bind Recombinant Human GFRAL Protein (His Tag) (Cat:27245-H08H), the EC50 is 10-30 ng/mL (QC tested) .

Function

Ala197-Ile308

Molecular Weight

The recombinant Human GDF-15 comprises 575 amino acids and has a predicted molecular mass of 62.5 kDa. It migrates as an approximately 64.8 kDa band in SDS-PAGE under reducing conditions. The molecular weight of this protein is around 134.5 kDa verified by SEC-MALS (Routinely tested) .