GDF15 Protein (N-human IgG1-Fc, Human)
Product Specifications
Abbreviation
GDF15
Synonyms
GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
Host
HEK 293
Tag
N-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 90 % as determined by SDS-PAGE
Bioactivity
Immobilized Recombinant Human GFRAL Protein (His Tag) (Mature Form) (Cat: 27245-H08H) at 2 μg/mL (100 μL/well) can bind Recombinant Human GDF-15 Protein (Fc Tag) (Cat: 10936-H01H), the EC50 is 50-150 ng/mL.
Function
Ala197-Ile308
Molecular Weight
The recombinant human Fc/GDF15 is a disulfide-linked homodimeric protein. The reduced monomer consists of 370 amino acids and has a predicted molecular mass of 40.6 kDa. rhGDF15/Fc monomer migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.
Species
Human
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