GDF15 Protein (N-human IgG1-Fc, Human)

Product Specifications

Abbreviation

GDF15

Synonyms

GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB

Host

HEK 293

Tag

N-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Immobilized Recombinant Human GFRAL Protein (His Tag) (Mature Form) (Cat: 27245-H08H) at 2 μg/mL (100 μL/well) can bind Recombinant Human GDF-15 Protein (Fc Tag) (Cat: 10936-H01H), the EC50 is 50-150 ng/mL.

Function

Ala197-Ile308

Molecular Weight

The recombinant human Fc/GDF15 is a disulfide-linked homodimeric protein. The reduced monomer consists of 370 amino acids and has a predicted molecular mass of 40.6 kDa. rhGDF15/Fc monomer migrates as an approximately 44 kDa protein in SDS-PAGE under reducing conditions.