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FGFR4 Protein (C-His, Human)

Product Specifications

Abbreviation

FGFR4

Synonyms

CD334, JTK2, TKF

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to inhibit FGF acidic (aFGF / FGF1) dependent proliferation of Balb/c3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.2-1μg/mL.

Function

Met1-Asp369

Molecular Weight

The secreted recombinant human FGFR4 consists of 359 amino acids and has a predicted molecular mass of 40 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh FGFR4 is approximately 60 kDa due to glycosylation.

Species

Human

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