FCGRT & B2M Protein (C-His, Cynomolgus)

1.Loaded Cynomolgus FcRn recombinant protein (Cat. CT031-C08H) on His1K Biosensor, can bind IgG1 Fc (Cat. 10702-HNAC) with an affinity constant of 0.032 μM as determined in a BLI assay (Sartorius Octet Red384) (Routinely tested) . 2.Captured Cynomolgus FcRn recombinant protein (Cat. CT031-C08H) on Anti-His Chip can bind Anti-VEGF (Research Grade Bevacizumab Biosimilar) (IgG1) with an affinity constant of 0.09 μM as determined in an SPR assay (Biacore T200) (Routinely tested) . 3.Captured Cynomolgus FcRn recombinant protein (Cat. CT031-C08H) on Anti-His Chip can bind Anti-PD1 (Research grade Nivolumab biosimilar) (IgG4) with an affinity constant of 0.18 μM as determined in an SPR assay (Biacore T200) (Routinely tested) . 4.Recombinant Cynomolgus FCGRT & B2M Heterodimer Protein (Cat: CT031-C08H) captured on CM5 chip via Anti-His antibody, can bind anti-ERBB2 (Research grade trastuz*mab biosimilar) with an affinity constant of 1.290 μM as determined in an SPR assay (Biacore 8K) (Routinely tested) .

The recombinant heterodimer of cynomolgus FCGRT&B2M comprises 384 (285+99) amino acids and has a calculated molecular mass of 43.5 (31.9+ 11.6) KDa. The apparent molecular mass of cynomolgus FCGRT&B2M heterodimer is approximately 35 & 12 KDa respectively in SDS-PAGE The molecular weight of this protein is around 40-60 kDa verified by SEC-MALS (Routinely tested) .