ERBB2 Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
ERBB2
Synonyms
C-ERB-2, c-ERB2, CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, MLN19, NEU, NGL, p185 (erbB2), TKR1, VSCN2
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 90 % as determined by SDS-PAGE
Bioactivity
Immobilized Her2/ERBB2 Protein, Human, Recombinant (hFc Tag), Biotinylated (Cat:10004-H02H-B) at 2 μg/ml (100 μl/well) can bind Anti-Erbb2 Antibody (Trastuzumab) (Cat:68046-H002), the EC50 is 20-110 ng/mL.
Function
Met1-Thr652
Molecular Weight
The recombinant human ErbB2/Fc chimera is a disulfide-linked homodimeric protein generated by proteolytic removal of the signal peptide. The monomer consists of 868 amino acids and predicts a molecular mass of 96.1 kDa.
Species
Human
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