ERBB2 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

ERBB2

Synonyms

C-ERB-2, c-ERB2, CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, MLN19, NEU, NGL, p185 (erbB2), TKR1, VSCN2

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Immobilized Her2/ERBB2 Protein, Human, Recombinant (hFc Tag), Biotinylated (Cat:10004-H02H-B) at 2 μg/ml (100 μl/well) can bind Anti-Erbb2 Antibody (Trastuzumab) (Cat:68046-H002), the EC50 is 20-110 ng/mL.

Function

Met1-Thr652

Molecular Weight

The recombinant human ErbB2/Fc chimera is a disulfide-linked homodimeric protein generated by proteolytic removal of the signal peptide. The monomer consists of 868 amino acids and predicts a molecular mass of 96.1 kDa.