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EPOR Protein (C-His, Human)

Product Specifications

Abbreviation

EPOR

Synonyms

EPO-R

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 98 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to inhibit EPO-dependent proliferation of TF-1 human erythroleukemic cells.The ED50 for this effect is typically 15-90 ng/mL in the presence of 0.1 U/mL Recombinant Human EPO.

Function

Ala25-Pro250

Molecular Weight

The secreted recombinant human EPOR consists of 237 amino acids and has a predicted molecular mass of 26.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhEPOR is approximately 34 kDa due to glycosylation.

Species

Human

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