EpCAM Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

EpCAM

Synonyms

17-1A,323/A3, Ber-Ep4, BerEp4, CD326, CO-17A, DIAR5, EGP-2, EGP314, EGP34, EGP40, Ep-CAM, EPCAM, ESA, GA733-2, HEA125, HNPCC8, KS1/4, KSA, Ly74, LYNCH8, M1S2, M4S1, MH99, MIC18, MK-1, MOC-31, MOC31, TACST-1, TACSTD1, TROP1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Human EpCAM / TROP-1 / TACSTD1 Protein (ECD, Fc Tag) (Cat: 10694-H02H) at 1 μg/mL (100 μL/well) can bind anti-EpCAM scFv-hIgG1 Fc, Biotinylated, the EC50 is 0.4-1.5 ng/mL (QC tested) .

Function

Met1-Lys265

Molecular Weight

The recombinant human EpCAM/Fc chimera is a disulfide-linked homodimeric protein after removal of the signal peptide. The monomer consists of 480 amino acids and has a calculated molecular mass of 54 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh EpCAM/Fc is approximately 65-70 kDa due to glycosylation.