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CLDN6 Protein (C-His-Flag, Human)

Product Specifications

Abbreviation

CLDN6

Synonyms

UNQ757/PRO1488

Host

HEK 293

Tag

C-His-Flag

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE

Bioactivity

1.Loaded Anti-CLDN6 antibody on ProA Biosensor, can bind Human CLDN6 Protein (Cat:16658-H61H-NA) with an affinity constant of 0.536nM as determined in BLI assay (Sartorius Octet Red384) (Routinely tested) . 2.Captured Anti-Human CLDN6 antibody on CM5 Chip via anti-human IgG Fc antibody, can bind Recombinant Human CLDN6-Nanodisc Protein (His & Flag Tag) (Cat:16658-H61H-NA) with an affinity constant of 7.03 nM as determined in a SPR assay (Biacore T200) (Routinely tested) . 3.Immobilized Recombinant Human CLDN6 Protein- (Nanodisc) (His & FLAG Tag) (Cat: 16658-H61H-NA) at 5 μg/mL (100 μL/well) can bind IMAB027-derived anti-Human CLDN6 Antibody, human IgG1, the EC50 is 2-10 ng/mL (QC tested) .

Function

Met1-Thr184

Molecular Weight

The recombinant human CLDN6 consists of 202 amino acids and has a predicted molecular mass of 21.87 kDa. The apparent molecular mass of it is approximately 20.91 KDa in SDS-PAGE under reducing conditions.

Species

Human

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