LAG3 Protein (Native, Human)
Product Specifications
Abbreviation
LAG3
Synonyms
CD223, FDC
Host
HEK 293
Tag
Native
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
1.Immobilized Recombinant Human LAG3/CD223 Protein, Biotinylated (ECD) (Cat: 16498-HNAH-B) at 2 μg/mL (100 μL/well) on streptavidin precoated (2 μg/mL, 100 μL/well) can bind Anti-LAG3 Antibody, the EC50 is 5-15 ng/mL. (QC tested) 2.Immobilized Recombinant Human LAG3/CD223 Protein, Biotinylated (ECD) (Cat: 16498-HNAH-B) at 2 μg/mL (100 μL/well) on streptavidin precoated (2 μg/mL, 100 μL/well) can bind Recombinant Human FGL1 Protein (His Tag) (Cat: 13484-H08B), the EC50 is 20-65 ng/mL. (routinely tested)
Function
Met1-Arg440
Molecular Weight
The recombinant human LAG3 consists of 418 amino acids and predicts a molecular mass of 45.3 kDa. As a result of glycosylation, it migrates as an approximately 47.0 KDa band in SDS-PAGE under non-reducing conditions.
Species
Human
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