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LAG3 Protein (Native, Human)

Product Specifications

Abbreviation

LAG3

Synonyms

CD223, FDC

Host

HEK 293

Tag

Native

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Recombinant Human LAG3/CD223 Protein, Biotinylated (ECD) (Cat: 16498-HNAH-B) at 2 μg/mL (100 μL/well) on streptavidin precoated (2 μg/mL, 100 μL/well) can bind Anti-LAG3 Antibody, the EC50 is 5-15 ng/mL. (QC tested) 2.Immobilized Recombinant Human LAG3/CD223 Protein, Biotinylated (ECD) (Cat: 16498-HNAH-B) at 2 μg/mL (100 μL/well) on streptavidin precoated (2 μg/mL, 100 μL/well) can bind Recombinant Human FGL1 Protein (His Tag) (Cat: 13484-H08B), the EC50 is 20-65 ng/mL. (routinely tested)

Function

Met1-Arg440

Molecular Weight

The recombinant human LAG3 consists of 418 amino acids and predicts a molecular mass of 45.3 kDa. As a result of glycosylation, it migrates as an approximately 47.0 KDa band in SDS-PAGE under non-reducing conditions.

Species

Human

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