IL12A & IL12B Protein (C-His, Human)
Product Specifications
Abbreviation
IL12A & IL12B
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 95 % as determined by SDS-PAGE.
Bioactivity
1.Immobilized Recombinant Human IL-12 R beta 2 / IL12RB2 Protein (ECD, His Tag) (Cat: 10145-H08H) at 5 μg/mL (100 μL/well) can bind Recombinant Human IL-12 (IL12A & IL12B Heterodimer) Protein, Biotinylated (Cat: CT011-H08H-B), the EC50 is 30-100 ng/mL (Routinely tested) . 2.Immobilized Recombinant Human IL-12 (IL12A & IL12B Heterodimer) Protein, Biotinylated (Cat: CT011-H08H-B) at 1 μg/mL (100 μL/well) on streptavidin precoated (5 μg/mL, 100 μL/well) plate can bind Anti-IL-12 & IL-23 (P40) (Research Grade Ustekin*mab Biosimilar), the EC50 is 1.1-3.5 ng/mL (Routinely tested) .
Function
Met1-Ser219 & Met1-Ser328
Molecular Weight
The recombinant IL12 heterodimer of human IL12A/IL12B comprises 525 (208 + 317) amino acids and has a calculated molecular mass of 60.13 (23.99+36.14) kDa.
Species
Human
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