FCGR3B Protein (C-AVI & His, Human)

Product Specifications

Abbreviation

FCGR3B

Synonyms

CD16, CD16-I, CD16A, CD16b, FCG3, FcgammaRIIIb, FCGR3, FCGR3A, FCR-10, FCRIII, FCRIIIb, IGFR3

Host

HEK 293

Tag

C-AVI & His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 95 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC

Bioactivity

Loaded Recombinant Human CD16b Protein (NA2 allotype, His&AVI Tag), Biotinylated (Cat: 11046-H27H-B) on SA Biosensor, can bind anti-VEGFA (Research grade Bevacizumab Biosimilar) with an affinity constant of 3.6 μM as determined in BLI assay (Sartorius Octet RED384) (QC tested) .

Function

Met1-Ser200

Molecular Weight

The recombinant human FCGR3B consists of 210 amino acids and predicts a molecular mass of 24.1 kDa. As a result of glycosylation, it migrates as an approximately 40-50 kDa band in SDS-PAGE under reducing conditions.