ERBB3 Protein (C-His, Human)
Product Specifications
Abbreviation
ERBB3
Synonyms
C-erbB-3, c-erbB3, ErbB-3, erbB3-S, FERLK, HER3, LCCS2, MDA-BF-1, p180-ErbB3, p45-sErbB3, p85-sErbB3, VSCN1
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
1.Immobilized Recombinant Human NRG1-beta 1 Protein (ECD, Fc Tag) (Cat: 11609-H01H2) at 2 μg/ml (100 μl/well) can bind Recombinant Human HER3 / ErbB3 Protein (ECD, His Tag) (Cat: 10201-H08H), the EC50 is 85-255 ng/mL (QC tested) . 2.Immobilized Anti-Human Her3 Antibody, Human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Human HER3 / ErbB3 Protein (ECD, His Tag) (Cat: 10201-H08H), the EC50 is 3-12 ng/mL (Rountinely tested) .
Function
Met1-Thr643
Molecular Weight
The recombinant human ErbB3 protein consists of 635 amino acids after the removal of signal peptide and has a calculated molecular mass of 70.2 kDa. As a result of glycosylation, the recombinant ErbB3 migrates as an approximately 100-110 kDa band in SDS-PAGE under reducing conditions.
Species
Human
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