FCGR3A Protein (C-His, Human)

Product Specifications

Abbreviation

FCGR3A

Synonyms

CD16, CD16-II, CD16A, FCG3, FcgammaRIIIa, FCGR3, FCGRIII, FcGRIIIA, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20

Host

CHO

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Loaded Recombinant Human CD16a / FCGR3A Protein (V176, His Tag) (Cat: 10389-H08C1) on His1K Biosensor, can bind anti-CD20 (Research grade Rituximab Biosimilar) with an affinity constant of 0.46 μM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met1-Gln208

Molecular Weight

The secreted recombinant human CD16a consists of 203 amino acids and predicts a molecular mass of 23.3 KDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rhCD16a is approximately 40-45 KDa due to glycosylation.