FCGR2A Protein (C-His, Human)
Product Specifications
Abbreviation
FCGR2A
Synonyms
CD32, CD32A, CDw32, Fc-gamma-RIIa, FCG2, FcgammaRIIa, FcGR, FCGR2, FCGR2A1, IGFR2
Host
CHO
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE.
Bioactivity
1. Loaded Recombinant Human CD32a / FCGR2A Protein (G167, His Tag) (Cat: 10374-H08C1) on His1K Biosensor, can bind anti-VEGFA (Research grade Bevacizumab Biosimilar) with an affinity constant of 0.62 μM as determined in BLI assay (Sartorius Octet RED384) (QC tested) . 2. Loaded Recombinant Human CD32a / FCGR2A Protein (G167, His Tag) (Cat: 10374-H08C1) on HIS1K Biosensor, can bind anti-CD20 (Research grade Rituximab Biosimilar) with an affinity constant of 5.6 μM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .
Function
Met1-Ile218
Molecular Weight
The secreted recombinant human CD32a consists of 196 amino acids and predicts a molecular mass of 22 KDa. The apparent molecular mass of the protein is approximately 29-32 KDa in SDS-PAGE under reducing conditions due to glycosylation.
Species
Human
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