CLEC12A Protein (N-His, Human)
Product Specifications
Abbreviation
CLEC12A
Synonyms
CD371, CLL-1, CLL1, DCAL-2, DCAL2, MICL
Host
HEK 293
Tag
N-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
1.Loaded Monoclonal anti-human CLL-1 Antibody, human IgG1 on ProA Biosensor, can bind Recombinant Human CLL-1/CLEC12A Protein, His Tag (Cat. No. 11896-H07H) with an affinity constant of 9.15 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Immobilized anti-CLL-1, Human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Human CLEC12A / CLL-1 / DCAL2 Protein (ECD, His Tag) (Cat: 11896-H07H), the EC50 is 15-45 ng/mL (Routinely tested) . 3.Immobilized Recombinant Human CLEC12A / CLL-1 / DCAL2 Protein (ECD, His Tag) (Cat: 11896-H07H) at 1 μg/mL (100 μL/well) can bind KITE-222 derived anti-CLL-1 antibody, human IgG1, the EC50 is 1.25-3.75 ng/mL (QC tested) .
Function
His75-Ala275
Molecular Weight
The recombinant human CLEC12A consists of 220 amino acids and has a calculated molecular mass of 26.06 kDa. The apparent molecular mass of rhCLEC12A is approximately 40-45 kDa in SDS-PAGE under reducing conditions.
Species
Human
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