TNFRSF9 Protein (C-His, Human)

Product Specifications

Abbreviation

TNFRSF9

Synonyms

4-1BB, CD137, CDw137, ILA, IMD109

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Measured by its binding ability in a functional ELISA. Immobilized Human 4-1BB-His (Cat: 10041-H08H) at 2 μg/ml (100 μl/well) can bind human 4-1BBL-hFc (Cat: 15693-H01H), the EC50 of human 4-1BBL-hFc is 8-40 ng/mL.

Function

Met1-Gln186

Molecular Weight

The recombinant human 4-1BB consists of 174 amino acids and has a calculated molecular mass of 18.8 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of human 4-1BB is approximately 30-35 kDa due to glycosylation.