PDCD1 Protein (C-His, Human)

Product Specifications

Abbreviation

PDCD1

Synonyms

CD279, hPD-1, hPD-l, hSLE1, PD-1, PD1, SLEB2

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Recombinant Human PD-1 Protein (C93S, His Tag) (Cat: 10377-H08H2) at 2 μg/mL (100 μL/well) can bind Recombinant Human PD-L1 / B7-H1 / CD274 Protein (Fc Tag) (Cat: 10084-H02H), the EC50 is 30-90 ng/mL (QC tested) . 2.Immobilized Recombinant Human PD-1 Protein (C93S, His Tag) (Cat: 10377-H08H2) at 1 μg/mL (100 μL/well) can bind Anti-PD1 (Research Grade Nivolu*mab Biosimilar), the EC50 is 1-5 ng/mL (QC tested) .

Function

Met1-Gln167

Molecular Weight

The recombinant Human PDCD1 consists of 154 amino acids and predicts a molecular mass of 17.38 kDa. It migrates as approximately 40.8 kDa band in SDS-PAGE under reducing conditions.