Melittin (free acid)
Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2) . Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3) -β-D-glucan synthase and participating in other pathways[1][2].
Product Specifications
CAS Number
123168-46-7
UNSPSC
12352209
Target
Apoptosis; Fungal; Phospholipase; Reactive Oxygen Species (ROS)
Type
Peptides
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/melittin-free-acid.html
Solubility
10 mM in DMSO
Smiles
Molecular Formula
C131H228N38O32
Molecular Weight
2847.45
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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