IL1R1/CD121a Protein (C-His-Fc, Rat)

Product Specifications

Abbreviation

IL1R1/CD121a

Synonyms

CD121 antigen-like family member A, CD121A, D2S1473, IL-1 RI, IL-1R-1, IL-1R-alpha, IL-1R1, IL-1RT-1, IL-1RT1, IL1R, IL1RA, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, P80

UniProt

A6INN1

Host

HEK 293

Tag

C-His-Fc

Applications

Cell culture

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 85 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its ability to inhibit IL1α-dependent proliferation in D10.G4. 1 mouse helper T cells (Symons, J. A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M. J. et al. (eds) : IRL Press. 272.) . The ED50 for this effect is typically 5-20 μg/ml in the presence of 40 pg/mL of recombinant human IL1a.