Rat CSF1R/CD115 Protein (C-hFc, Rat)

Product Specifications

Abbreviation

Rat CSF1R/CD115

Synonyms

CSF1R, MCSF Receptor

UniProt

D4ACA7

Host

HEK 293

Tag

C-hFc

Applications

Cell culture, ELISA

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

1. Immobilized rat CSF1R-Fc at 10 μg/ml (100 μl/well) can bind biotinylated human CSF1-His, The EC50 of biotinylated human CSF1-His is 1.7-3.9 ng/ml. 2. Measured by its ability to inhibit mouse CSF induced proliferation of M‐NFS‐60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.015-0.06 μg/mL in the presence of 2. 5 ng/ml Recombinant Mouse M-CSF.