Osteoprotegerin/TNFRSF11B Protein (C-His, Human)
Product Specifications
Abbreviation
Osteoprotegerin/TNFRSF11B
Synonyms
OCIF, OPG, Osteoclastogenesis inhibitory factor, Osteoprotegerin, PDB5, TNFRSF11B, TR1 , Tumor necrosis factor receptor superfamily member 11B
UniProt
O00300
Host
HEK 293
Tag
C-His
Applications
Cell culture, ELISA
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 97 % as determined by reducing SDS-PAGE.
Bioactivity
1. Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is typically 5-20 ng/mL in the presence of 20 ng/mL Recombinant Human TRAIL/TNFSF10. 2. Immobilized human TNFRSF11B-His at 10 μg/ml (100 μl/well) can bind human Fc-TNFSF11 with a linear ranger of 3. 125-200 ng/mL.
Function
Met 1-Leu 401
Molecular Weight
45.3 kDa
Species
Human
Curated Selection
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