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TIMP-1/TIMP1 Protein (C-His, Human)

Product Specifications

Abbreviation

TIMP-1/TIMP1

Synonyms

CLGI, Collagenase Inhibitor, EPA, EPO, Erythroid-Potentiating Activity, Fibroblast collagenase Inhibitor, HCI, Metalloproteinase Inhibitor 1, TIMP, TIMP-1, TIMP1, Tissue Inhibitor of Metalloproteinases 1

UniProt

P01033

Host

HEK 293

Tag

C-His

Applications

Enzyme

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 97 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate MCA-PLGL-DPA-AR-NH2 (R&D Systems, Catalog # ES001) . The IC50 value is < 6 nM.

Function

Met 1-Ala 207

Molecular Weight

22 kDa

Species

Human

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