TIMP-1/TIMP1 Protein (Human)
Product Specifications
Abbreviation
TIMP-1/TIMP1
Synonyms
CLGI, Collagenase Inhibitor, EPA, EPO, Erythroid-Potentiating Activity, Fibroblast collagenase Inhibitor, HCI, Metalloproteinase Inhibitor 1, TIMP, TIMP-1, TIMP1, Tissue Inhibitor of Metalloproteinases 1
UniProt
P01033
Host
HEK 293
Applications
Enzyme
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 97 % as determined by reducing SDS-PAGE.
Bioactivity
Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate MCA-PLGL-DPA-AR-NH2 (R&D Systems, Catalog # ES001) . The IC50 value is < 6 nM.
Function
Cys 24-Ala 207
Molecular Weight
21 kDa
Species
Human
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