CSF1R/CD115 Protein (Human)

Product Specifications

Abbreviation

CSF1R/CD115

Synonyms

C-FMS, CD115, CSF-1 receptor, CSF-1-R, CSF-1R, CSF1R, FIM2, FMS, HDLS, M-CSF-R, MCSF Receptor , Macrophage colony-stimulating factor 1 receptor, Proto-oncogene c-Fms

UniProt

P07333

Host

HEK 293

Applications

Cell culture, ELISA

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

1. Immobilized sMCSFR at 10 μg/ml (100 μl/well) can bind biotinylated human CSF1-His, The EC50 of biotinylated human CSF1-His is 32-74. 8 ng/ml. 2. Measured by its ability to inhibit the human CSF-induced proliferation of M‐NFS‐60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.3-1. 5 μg/mL in the presence of 3 ng/mL of rhM-CSF.