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HMGB1/HMG1 Protein (C-His, Human)

Product Specifications

Abbreviation

HMGB1/HMG1

Synonyms

HMG-1, HMG1, HMG3, SBP-1

UniProt

P09429

Host

HEK 293

Tag

C-His

Applications

Cell culture, ELISA

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 93 % as determined by reducing SDS-PAGE.

Bioactivity

1. Immobilized human HMGB at 2 μg/ml (100 μl/well) can bind human AGER. The EC50 of human AGER is 0.27 μg/ml. 2. Measured by its ability to induce TNF-alpha secretion by RAW 264. 7 mouse monocyte/macrophage cells. The EC50 for this effect is typically 20-100μg/ml.

Function

Met 1-Glu 215

Molecular Weight

26.3 kDa

Species

Human

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