CD122/IL-2RB Protein (Human)

Product Specifications

Abbreviation

CD122/IL-2RB

Synonyms

P70, IL2RB, CD122, IL15RB, P70-75, IL-2Rβ, p75, IL-2RB, Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, High affinity IL-2 receptor subunit beta, Interleukin-15 receptor subunit beta, p70-75 (p75), IL-2R&amp, beta, CD122 antigen, High affinity IL 2 receptor beta subunit, High affinity IL 2 receptor subunit beta, IL2 receptor, Interleukin 2 receptor beta, interleukin 2 receptor subunit beta, P70 75, P7075

UniProt

P14784

Host

HEK 293

Applications

Cell culture, ELISA

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

1. Immobilized human IL2Rb at 10 μg/ml (100 μl/well) can bind biotinylated human IL2, The EC50 of biotinylated human IL2 is 0.1-0.24 μg/mL. 2. Measured by its ability to inhibit IL15-dependent proliferation of MO7e human megakaryocytic leukemic cells in the presence of 4.0 ng/mL of recombinant human IL-15.The ED50 for this effect is 1-4μg/mL.