TNFR1; TNFRSF1A Protein (C-Fc, Human)
Product Specifications
Abbreviation
TNFR1; TNFRSF1A
Synonyms
TNF-R1, TNF-RI, TNFAR, TNFR-I, TNFR1, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor type I
UniProt
P19438
Host
HEK 293
Tag
C-Fc
Applications
Cell culture
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Measured by its ability to induce NF-κB reporter activity in HEK293 human embryonic kidney cells. Recombinant Human TNF RI inhibits a constant dose of 0.5ng/mL of Recombinant TNF alpha. The IC50 for this effect is 2.7 ng/mL.
Function
Leu30-Thr 211
Molecular Weight
47.2 kDa
Species
Human
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