TNFRSF1B/CD120b Protein (C-His, Human)
Product Specifications
Abbreviation
TNFRSF1B/CD120b
Synonyms
CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
UniProt
P20333
Host
HEK 293
Tag
C-His
Applications
Cell culture
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Measured by its ability to inhibit TNF-α mediated cytotoxicity in L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 5-40 ng/mL in the presence of 1 ng/mL recombinant human TNF-α.
Function
Met 1-Arg268, natural variant 196 Met/Arg
Molecular Weight
27.7 kDa
Species
Human
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