TNFRSF1B/CD120b Protein (C-His, Mouse)

Product Specifications

Abbreviation

TNFRSF1B/CD120b

Synonyms

CD120b, TNF-R-II, TNF-R2, TNF-R75, TNF-alphaR2, TNFBR, TNFR80, TNFRII, TNFalpha-R2, Tnfr-1, Tnfr2, Tnfrsf1b, Tumor necrosis factor receptor superfamily member 1b, p75

UniProt

P25119

Host

HEK 293

Tag

C-His

Applications

Cell culture

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 97 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its ability to inhibit TNFα-mediated cytotoxicity in L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 1-3 μg/mL in the presence of 0.1 ng/mL of recombinant mouse TNFα.