Activin Receptor 2B/ACVR2B Protein (C-His-Fc, Mouse)

Product Specifications

Abbreviation

Activin Receptor 2B/ACVR2B

Synonyms

4930516B21Rik, ActRIIB

UniProt

P27040

Host

HEK 293

Tag

C-His-Fc

Applications

Cell culture

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 97 % as determined by reducing SDS-PAGE.

Bioactivity

1. Measured by its ability to bind biotinylated Human INHBA-his and biotinylated mouse INHBA-his in functional ELISA. 2. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 10-50 ng/mL in the presence of 10 ng/mL recombinant Activin A.