Activin Receptor 2B/ACVR2B Protein (C-His, Mouse)
Product Specifications
Abbreviation
Activin Receptor 2B/ACVR2B
Synonyms
4930516B21Rik, ActRIIB
UniProt
P27040
Host
HEK 293
Tag
C-His
Applications
Cell culture, ELISA
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 94 % as determined by reducing SDS-PAGE.
Bioactivity
1. Immobilized human ACVR2B at 10 μg/mL (100 μl/well) can bind biotinylated mouse INHBA-His, The EC50 of biotinylated mouse INHBA-His is 0.161 μg/mL. 2. Immobilized mouse INHBA-his at 10 μg/mL (100 μl/well) can bind human Follistatin Protein, The EC50 of human Follistatin Protein is 0.39 μg/mL. 3. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-0.8 μg/mL in the presence of 10 ng/mL recombinant Activin A.
Function
Met 1-Thr 134
Molecular Weight
14.8 kDa
Species
Mouse
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