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Activin Receptor 2B/ACVR2B Protein (C-His, Mouse)

Product Specifications

Abbreviation

Activin Receptor 2B/ACVR2B

Synonyms

4930516B21Rik, ActRIIB

UniProt

P27040

Host

HEK 293

Tag

C-His

Applications

Cell culture, ELISA

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 94 % as determined by reducing SDS-PAGE.

Bioactivity

1. Immobilized human ACVR2B at 10 μg/mL (100 μl/well) can bind biotinylated mouse INHBA-His, The EC50 of biotinylated mouse INHBA-His is 0.161 μg/mL. 2. Immobilized mouse INHBA-his at 10 μg/mL (100 μl/well) can bind human Follistatin Protein, The EC50 of human Follistatin Protein is 0.39 μg/mL. 3. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-0.8 μg/mL in the presence of 10 ng/mL recombinant Activin A.

Function

Met 1-Thr 134

Molecular Weight

14.8 kDa

Species

Mouse

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